The Thermodynamic Solvers (P-THERMAL) enable the modeling of heat transfer in living tissue using advanced perfusion and thermoregulation models. The two solvers adapted from SEMCAD X are based on 1) the finite-difference time-domain solver with conformal surface correction and 2) a steady-state finite volume solver to support adaptive rectilinear meshes and arbitrary active domain shapes.
Contents
  • The solvers allow for the coupled simulation of local vascular effects using discrete networks (1D trees) and, in the near future, CFD results.
  • Exclusive thermal damage and effect quantification models, e.g., T-CEM43, are included.
  • The P-THERMAL solvers have been extensively validated by comparison with analytically solvable cases, experimental measurements under controlled conditions, and in vivo measurements.
Applications
  • MRI Tx RF Coil Design w/ Gradient Interaction & Safety
  • Active & Passive Implants MRI Safety
  • RF Hyperthermia
  • Safety & Efficacy Assessment of Ultrasonic Devices for Therapeutic Purposes
  • RF/MW Tumor Ablation, RF Surgery
  • Design & Optimization of Ultrasonic Devices for Therapeutic Purposes
  • MRgFUS Neurosurgery Applications: Tumor Ablation, Neuropathic Pain Treatment, Movement Disorders
  • Hypothermia
  • Cryosurgery
  • Temperature Impact on Neuronal Dynamics
  • Flow in Eye (oxygenation, heating)
  • Local Cooling by Blood
Characteristics
  • T standalone solver
  • Coupled EM-T, extended Pennes Bioheat Equation for BioEM
  • Discrete vessel model for BioEM
  • Steady state T solver
  • Multiple EM sources (not bound to single simulation)
  • Correlated/uncorrelated superposition of fields, individual scaling
  • Pulsed excitation/time profile, on-off switch
  • T dependent tissues (electric conductivity, SAR, blood perfusion)
  • Time dependent specific heat generation rates
  • Tensorial heat diffusion
  • Spline-based vessels
  • Conformal subcell T solver
  • Flexible boundary-conditions (Neumann, Dirichlet, mixed, for every interface and every direction)
  • Extended T solver functionality (field optimization extended features)
  • Thermal ablation (tissue damage) measure
  • Convective flow term
  • LF solver results as T sources
  • Field statistics for T results

  • Product list