SEMCAD X Matterhorn offers high-performance computing (HPC) for investigation of complex and realistic models. Multi-threaded execution for modeling, meshing, voxeling, and postprocessing enables parallel processing of heavy tasks without disturbing the workflow. A fully integrated centralized task manager efficiently manages all computationally intensive tasks on the local machine or in the cloud. Two sets of CUDA-based libraries for GPU acceleration, Acceleware and SPEAG CUDA, are provided.